Autoantibodies to malondialdehyde-modified epitope in connective tissue diseases and vasculitides.

Malondialdehyde (MDA), a peroxidative end-product released during polyunsaturated fatty acid degradation, reacts strongly with lysine residues of cellular proteins. MDA-modified proteins become immunogenic and may elicit specific autoantibody formation. We hypothesized that systemic diseases in whic...

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Autori principali: Amara, A, Constans, J, Chaugier, C, Sebban, A, Dubourg, L, Peuchant, E, Pellegrin, J L, Leng, B, Conri, C, Geffard, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553266/
https://ncbi.nlm.nih.gov/pubmed/7544246
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