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Fibronectin (FN) decreases glomerular lesions and synthesis of tumour necrosis factor-alpha (TNF-alpha), platelet-activating factor (PAF) and FN in proliferative glomerulonephritis.

We have studied the effect of therapy with plasma FN on glomerular synthesis of PAF, TNF-alpha and FN, in experimental proliferative glomerulonephritis. Glomerular PAF, TNF-alpha and FN production were increased in rats with nephritis. Peak glomerular PAF production preceded, while peak glomerular T...

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Dettagli Bibliografici
Autori principali: Ortíz, A, Alonso, J, Gómez-Chiarri, M, Lerma, J L, Seron, D, Condom, E, González, E, Egido, J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1553248/
https://ncbi.nlm.nih.gov/pubmed/7648718
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