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Hypertrophic growth in cardiac myocytes is mediated by Myc through a Cyclin D2-dependent pathway
c-Myc (Myc) is highly expressed in developing embryos where it regulates body size by controlling proliferation but not cell size. However, Myc is also induced in many postmitotic tissues, including adult myocardium, in response to stress where the predominant form of growth is an increase in cell s...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1553193/ https://ncbi.nlm.nih.gov/pubmed/16902412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601252 |
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