Regulation of selectin binding activity by cyclization of sialic acid moiety of carbohydrate ligands on human leukocytes

We provide here evidence that supports the occurrence of a biologically dormant form of selectin ligand carbohydrate, the sialyl 6-sulfo Lewis X containing modified sialic acid, in human leukocytes. The modification of sialic acid involves first de-N-acetylation of sialic acid moiety through ubiquit...

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Bibliografiske detaljer
Main Authors: Mitsuoka, Chikako, Ohmori, Katsuyuki, Kimura, Naoko, Kanamori, Akiko, Komba, Shiro, Ishida, Hideharu, Kiso, Makoto, Kannagi, Reiji
Format: Artigo
Sprog:Inglês
Udgivet: The National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC15530/
https://ncbi.nlm.nih.gov/pubmed/9990070
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