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Doxapram Only Slightly Reduces the Shivering Threshold in Healthy Volunteers

We determined the effects of doxapram on the major autonomic thermoregulatory responses in humans. Nine healthy volunteers were studied on two days: Control and Doxapram (intravenous infusion to a plasma concentration of 2.4 ±0.8 μg/mL, 2.5 ±0.9 μg/mL, and 2.6 ±1.1 μg/mL at the sweating, vasoconstri...

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Detalhes bibliográficos
Main Authors: Komatsu, Ryu, Sengupta, Papiya, Cherynak, Grigory, Wadhwa, Anupama, Sessler, Daniel I., Liu, Jin, Hurst, Harrell E., Lenhardt, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1552102/
https://ncbi.nlm.nih.gov/pubmed/16243996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1213/01.ANE.0000180198.13467.DF
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