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Computing Ka and Ks with a consideration of unequal transitional substitutions

BACKGROUND: Approximate methods for estimating nonsynonymous and synonymous substitution rates (Ka and Ks) among protein-coding sequences have adopted different mutation (substitution) models. In the past two decades, several methods have been proposed but they have not considered unequal transition...

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Hlavní autoři: Zhang, Zhang, Li, Jun, Yu, Jun
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1552089/
https://ncbi.nlm.nih.gov/pubmed/16740169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-6-44
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