Cooperation of the Inducible Nitric Oxide Synthase and Cytochrome P450 1A1 in Mediating Lung Inflammation and Mutagenicity Induced by Diesel Exhaust Particles

Diesel exhaust particles (DEPs) have been shown to activate oxidant generation by alveolar macrophages (AMs), alter xenobiotic metabolic pathways, and modify the balance of pro-antiinflammatory cytokines. In this study we investigated the role of nitric oxide (NO) in DEP-mediated and DEP organic ext...

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Bibliografiske detaljer
Main Authors: Zhao, Hongwen, Barger, Mark W., Ma, Joseph K.H., Castranova, Vincent, Ma, Jane Y.C.
Format: Artigo
Sprog:Inglês
Udgivet: National Institute of Environmental Health Sciences 2006
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1552032/
https://ncbi.nlm.nih.gov/pubmed/16882535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9063
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