Binding of Human Cytomegalovirus US2 to Major Histocompatibility Complex Class I and II Proteins Is Not Sufficient for Their Degradation

Human cytomegalovirus (HCMV) glycoprotein US2 causes degradation of major histocompatibility complex (MHC) class I heavy-chain (HC), class II DR-α and DM-α proteins, and HFE, a nonclassical MHC protein. In US2-expressing cells, MHC proteins present in the endoplasmic reticulum (ER) are degraded by c...

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Detalles Bibliográficos
Main Authors: Chevalier, Mathieu S., Daniels, Gwynn M., Johnson, David C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2002
Assuntos:
Virus-Cell Interactions
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC155152/
https://ncbi.nlm.nih.gov/pubmed/12134032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.16.8265-8275.2002
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