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Novel Role of CD8(+) T Cells and Major Histocompatibility Complex Class I Genes in the Generation of Protective CD4(+) Th1 Responses during Retrovirus Infection in Mice

CD4(+) Th1 responses to virus infections are often necessary for the development and maintenance of virus-specific CD8(+) T-cell responses. However, in the present study with Friend murine retrovirus (FV), the reverse was also found to be true. In the absence of a responder H-2(b) allele at major hi...

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Autors principals: Peterson, Karin E., Stromnes, Ingunn, Messer, Ron, Hasenkrug, Kim, Chesebro, Bruce
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155146/
https://ncbi.nlm.nih.gov/pubmed/12133998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.16.7942-7948.2002
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