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Critical Role for Protein Tyrosine Phosphatase SHP-1 in Controlling Infection of Central Nervous System Glia and Demyelination by Theiler's Murine Encephalomyelitis Virus

We previously characterized the expression and function of the protein tyrosine phosphatase SHP-1 in the glia of the central nervous system (CNS). In the present study, we describe the role of SHP-1 in virus infection of glia and virus-induced demyelination in the CNS. For in vivo studies, SHP-1-def...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Massa, Paul T., Ropka, Stacie L., Saha, Sucharita, Fecenko, Karen L., Beuler, Kathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155140/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12134038/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.16.8335-8346.2002
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