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Wiring optimization can relate neuronal structure and function

We pursue the hypothesis that neuronal placement in animals minimizes wiring costs for given functional constraints, as specified by synaptic connectivity. Using a newly compiled version of the Caenorhabditis elegans wiring diagram, we solve for the optimal layout of 279 nonpharyngeal neurons. In th...

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書目詳細資料
Main Authors: Chen, Beth L., Hall, David H., Chklovskii, Dmitri B.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550972/
https://ncbi.nlm.nih.gov/pubmed/16537428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0506806103
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