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NK T Cells Contribute to Expansion of CD8(+) T Cells and Amplification of Antiviral Immune Responses to Respiratory Syncytial Virus

CD1d-deficient mice have normal numbers of T lymphocytes and natural killer cells but lack Vα14(+) natural killer T cells. Respiratory syncytial virus (RSV) immunopathogenesis was evaluated in 129×C57BL/6, C57BL/6, and BALB/c CD1d(−/−) mice. CD8(+) T lymphocytes were reduced in CD1d(−/−) mice of all...

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Autors principals: Johnson, Teresa R., Hong, Seokmann, Van Kaer, Luc, Koezuka, Yasuhiko, Graham, Barney S.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC155085/
https://ncbi.nlm.nih.gov/pubmed/11932395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.9.4294-4303.2002
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