The ITAM in Nef Influences Acute Pathogenesis of AIDS-Inducing Simian Immunodeficiency Viruses SIVsm and SIVagm without Altering Kinetics or Extent of Viremia

The role of the immunoreceptor tyrosine-based activation motif (ITAM) that is unique to the Nef protein of the acutely pathogenic simian immunodeficiency virus SIVsmPBj was studied in the context of two AIDS-inducing simian immunodeficiency virus molecular clones. NefY(+) variants of SIVagm9063-2 an...

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Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Dehghani, Houman, Brown, Charles R., Plishka, Ronald, Buckler-White, Alicia, Hirsch, Vanessa M.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 2002
Предметы:	Pathogenesis and Immunity
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC155068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11932405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.9.4379-4389.2002
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