The tert-butylhydroquinone-mediated activation of the human thioredoxin gene reveals a novel promoter structure

Thioredoxin is a redox-active protein that plays multiple roles in regulating cell growth, cell signalling and apoptosis. Here, we have demonstrated that a complex mechanism involving multiple regulatory elements is involved in the tBHQ [tert-butylhydroquinone or 2,5-di-(t-butyl)-1,4-hydroquinone]-m...

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Detalhes bibliográficos
Main Authors: Osborne, Simone A., Hawkes, Hye-Jin Kim, Baldwin, Ben L., Alexander, Kylie A., Svingen, Terje, Clarke, Frank M., Tonissen, Kathryn F.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550307/
https://ncbi.nlm.nih.gov/pubmed/16712525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20060076
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