Solitary Lung Tumors and Their Spontaneous Metastasis in Athymic Nude Mice Orthotopically Implanted with Human Non-Small Cell Lung Cancer

We examined the tumorigenic and metastatic potentials of three human non-small cell lung cancer (NSCLC) cell lines. PC-14, A549 or Lu-99 cell lines suspended in Matrigel-containing phosphate-buffered saline were orthotopically implanted into the lungs of nude mice. The formation of a solitary tumor...

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Bibliographic Details
Main Authors: Yamaura, Takeshi, Murakami, Koji, Doki, Yoshinori, Sugiyama, Shigeki, Misaki, Takuro, Yamada, Yuji, Saiki, Ikuo
Format: Artigo
Language:Inglês
Published: Nature America, Inc. 2000
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550292/
https://ncbi.nlm.nih.gov/pubmed/11005566
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