Novel STAT1 Alleles in Otherwise Healthy Patients with Mycobacterial Disease

The transcription factor signal transducer and activator of transcription-1 (STAT1) plays a key role in immunity against mycobacterial and viral infections. Here, we characterize three human STAT1 germline alleles from otherwise healthy patients with mycobacterial disease. The previously reported L7...

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Autors principals: Chapgier, Ariane, Boisson-Dupuis, Stéphanie, Jouanguy, Emmanuelle, Vogt, Guillaume, Feinberg, Jacqueline, Prochnicka-Chalufour, Ada, Casrouge, Armanda, Yang, Kun, Soudais, Claire, Fieschi, Claire, Santos, Orchidée Filipe, Bustamante, Jacinta, Picard, Capucine, de Beaucoudrey, Ludovic, Emile, Jean-François, Arkwright, Peter D, Schreiber, Robert D, Rolinck-Werninghaus, Claudia, Rösen-Wolff, Angela, Magdorf, Klaus, Roesler, Joachim, Casanova, Jean-Laurent
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2006
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1550284/
https://ncbi.nlm.nih.gov/pubmed/16934001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020131
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