Characterization of a Conformational Epitope on Hepatitis B Virus Core Antigen and Quasiequivalent Variations in Antibody Binding

We have characterized a conformational epitope on capsids of hepatitis B virus (HBV) by cryo-electron microscopy and three-dimensional image reconstruction of Fab-labeled capsids to ∼10-Å resolution, combined with molecular modeling. The epitope straddles the interface between two adjacent subunits...

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Detalles Bibliográficos
Main Authors: Conway, J. F., Watts, N. R., Belnap, D. M., Cheng, N., Stahl, S. J., Wingfield, P. T., Steven, A. C.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Structure and Assembly
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC155010/
https://ncbi.nlm.nih.gov/pubmed/12743303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.11.6466-6473.2003
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