Comparative Immunogenicity in Rhesus Monkeys of DNA Plasmid, Recombinant Vaccinia Virus, and Replication-Defective Adenovirus Vectors Expressing a Human Immunodeficiency Virus Type 1 gag Gene

Cellular immune responses, particularly those associated with CD3(+) CD8(+) cytotoxic T lymphocytes (CTL), play a primary role in controlling viral infection, including persistent infection with human immunodeficiency virus type 1 (HIV-1). Accordingly, recent HIV-1 vaccine research efforts have focu...

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Main Authors: Casimiro, Danilo R., Chen, Ling, Fu, Tong-Ming, Evans, Robert K., Caulfield, Michael J., Davies, Mary-Ellen, Tang, Aimin, Chen, Minchun, Huang, Lingyi, Harris, Virginia, Freed, Daniel C., Wilson, Keith A., Dubey, Sheri, Zhu, De-Min, Nawrocki, Denise, Mach, Henryk, Troutman, Robert, Isopi, Lynne, Williams, Donna, Hurni, William, Xu, Zheng, Smith, Jeffrey G., Wang, Su, Liu, Xu, Guan, Liming, Long, Romnie, Trigona, Wendy, Heidecker, Gwendolyn J., Perry, Helen C., Persaud, Natasha, Toner, Timothy J., Su, Qin, Liang, Xiaoping, Youil, Rima, Chastain, Michael, Bett, Andrew J., Volkin, David B., Emini, Emilio A., Shiver, John W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC154996/
https://ncbi.nlm.nih.gov/pubmed/12743287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.11.6305-6313.2003
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