Improvement of Differentiation and Interpretability of Spoligotyping for Mycobacterium tuberculosis Complex Isolates by Introduction of New Spacer Oligonucleotides

The direct repeat (DR) region in Mycobacterium tuberculosis complex strains is composed of multiple well-conserved 36-bp DRs interspersed with nonrepetitive DNA spacer sequences of similar size. Clinical isolates show extensive polymorphism in this DR region, and this has led to the development of a...

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Библиографические подробности
Главные авторы: van der Zanden, A. G. M., Kremer, K., Schouls, L. M., Caimi, K., Cataldi, A., Hulleman, A., Nagelkerke, N. J. D., van Soolingen, D.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology (ASM) 2002
Предметы:
Mycobacteriology and Aerobic Actinomycetes
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC154657/
https://ncbi.nlm.nih.gov/pubmed/12454164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.40.12.4628-4639.2002
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