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Mammalian subtilisin/kexin isozyme SKI-1: A widely expressed proprotein convertase with a unique cleavage specificity and cellular localization

Using reverse transcriptase–PCR and degenerate oligonucleotides derived from the active-site residues of subtilisin/kexin-like serine proteinases, we have identified a highly conserved and phylogenetically ancestral human, rat, and mouse type I membrane-bound proteinase called subtilisin/kexin-isozy...

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Auteurs principaux: Seidah, Nabil G., Mowla, Seyed J., Hamelin, Josée, Mamarbachi, Aida M., Benjannet, Suzanne, Touré, Barry B., Basak, Ajoy, Munzer, Jon Scott, Marcinkiewicz, Jadwiga, Zhong, Mei, Barale, Jean-Christophe, Lazure, Claude, Murphy, Richard A., Chrétien, Michel, Marcinkiewicz, Mieczyslaw
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC15461/
https://ncbi.nlm.nih.gov/pubmed/9990022
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