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Modification of Sm small nuclear RNAs occurs in the nucleoplasmic Cajal body following import from the cytoplasm

Biogenesis of functional spliceosomal small nuclear RNAs (snRNAs) includes the post-transcriptional covalent modification of numerous internal nucleotides. We have recently demonstrated that synthesis of 2′-O-methylated nucleotides and pseudouridines in the RNA polymerase II-synthesized Sm snRNAs is...

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Detalhes bibliográficos
Main Authors: Jády, Beáta E., Darzacq, Xavier, Tucker, Karen E., Matera, A.Gregory, Bertrand, Edouard, Kiss, Tamás
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154478/
https://ncbi.nlm.nih.gov/pubmed/12682020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg187
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