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The yeast Sgs1 helicase is differentially required for genomic and ribosomal DNA replication

The members of the RecQ family of DNA helicases play conserved roles in the preservation of genome integrity. RecQ helicases are implicated in Bloom and Werner syndromes, which are associated with genomic instability and predisposition to cancers. The human BLM and WRN helicases are required for nor...

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Main Authors: Versini, Gwennaelle, Comet, Itys, Wu, Michelle, Hoopes, Laura, Schwob, Etienne, Pasero, Philippe
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC154472/
https://ncbi.nlm.nih.gov/pubmed/12682026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg180
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