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Principles of quasi-equivalence and Euclidean geometry govern the assembly of cubic and dodecahedral cores of pyruvate dehydrogenase complexes

The pyruvate dehydrogenase multienzyme complex (M(r) of 5–10 million) is assembled around a structural core formed of multiple copies of dihydrolipoyl acetyltransferase (E2p), which exhibits the shape of either a cube or a dodecahedron, depending on the source. The crystal structures of the 60-meric...

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Detalhes bibliográficos
Main Authors: Izard, Tina, Ævarsson, Arnthor, Allen, Mark D., Westphal, Adrie H., Perham, Richard N., de Kok, Aart, Hol, Wim G. J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15447/
https://ncbi.nlm.nih.gov/pubmed/9990008
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