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FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals

Fibroblast growth factors (FGFs) are signaling molecules of the isthmic organizer, which regulates development of the midbrain and cerebellum. Tissue-specific inactivation of one of the FGF receptor (FGFR) genes, Fgfr1, in the midbrain and rhombomere 1 of the hindbrain of mouse embryos results in de...

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Main Authors: Trokovic, Ras, Trokovic, Nina, Hernesniemi, Sanna, Pirvola, Ulla, Vogt Weisenhorn, Daniela M., Rossant, Janet, McMahon, Andrew P., Wurst, Wolfgang, Partanen, Juha
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC154461/
https://ncbi.nlm.nih.gov/pubmed/12682014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg169
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