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Drug-Induced Torsade de Pointes and Implications for Drug Development

Torsade de pointes is a potentially lethal arrhythmia that occasionally appears as an adverse effect of pharmacotherapy. Recently-developed understanding of the underlying electrophysiology allows better estimation of the drug-induced risks, and explains the failures of older approaches through the...

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Main Authors: Fenichel, Robert R., Malik, Marek, Antzelevitch, Charles, Sanguinetti, Michael, Roden, Dan M., Priori, Silvia G., Ruskin, Jeremy N., Lipicky, Raymond J., Cantilena, Lou
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544371/
https://ncbi.nlm.nih.gov/pubmed/15090000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1540-8167.2004.03534.x
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