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Exposure to receptor-activator of NFκB ligand renders pre-osteoclasts resistant to IFN-γ by inducing terminal differentiation

While it has been established that IFN-γ is a strong activator of macrophages and a potent inhibitor of osteoclastogenesis in vitro, it is also known that this cytokine is produced in particular settings of inflammatory bone loss, such as infection and psoriatic arthritis. Because of the different k...

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Publicado en:Arthritis Res Ther
Principais autores: Huang, Willis, O'Keefe, Regis J, Schwarz, Edward M
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2002
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154432/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12716453/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/ar612
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