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Funneled Landscape Leads to Robustness of Cellular Networks: MAPK Signal Transduction
We uncover the underlying potential energy landscape for a cellular network. We find that the potential energy landscape of the mitogen-activated protein-kinase signal transduction network is funneled toward the global minimum. The funneled landscape is quite robust against random perturbations. Thi...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Biophysical Society
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1544318/ https://ncbi.nlm.nih.gov/pubmed/16815898 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.086777 |
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