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Amyloid Fibrils of Glucagon Characterized by High-Resolution Atomic Force Microscopy

Glucagon solutions at pH 2.0 were subjected to mechanical agitation at 37°C in the presence of a hydrophobic surface to explore the details of aggregation and fiber formation. High-resolution intermittent-contact atomic force microscopy performed in solution revealed the presence of aggregates after...

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Detalhes bibliográficos
Main Authors: De Jong, Kathy L., Incledon, Bev, Yip, Christopher M., DeFelippis, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544305/
https://ncbi.nlm.nih.gov/pubmed/16766610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.077438
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