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Topical vitamin D3 and low-calcemic analogs induce thymic stromal lymphopoietin in mouse keratinocytes and trigger an atopic dermatitis

We have demonstrated that cytokine thymic stromal lymphopoietin (TSLP), whose expression is rapidly induced upon keratinocyte-selective ablation of retinoid X receptors (RXRs) -α and -β in the mouse (RXRαβ(ep−/−) mice), plays a key role in initiating a skin and systemic atopic dermatitis-like phenot...

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Hlavní autoři: Li, Mei, Hener, Pierre, Zhang, Zhikun, Kato, Shigeaki, Metzger, Daniel, Chambon, Pierre
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544239/
https://ncbi.nlm.nih.gov/pubmed/16880407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604575103
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