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Nitric oxide inhibits exocytosis of cytolytic granules from lymphokine-activated killer cells

NO inhibits cytotoxic T lymphocyte killing of target cells, although the precise mechanism is unknown. We hypothesized that NO decreases exocytosis of cytotoxic granules from activated lymphocytes. We now show that NO inhibits lymphokine-activated killer cell killing of K562 target cells. Exogenous...

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Detalhes bibliográficos
Main Authors: Ferlito, Marcella, Irani, Kaikobad, Faraday, Nauder, Lowenstein, Charles J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544231/
https://ncbi.nlm.nih.gov/pubmed/16857739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600275103
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