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CDC7 kinase phosphorylates serine residues adjacent to acidic amino acids in the minichromosome maintenance 2 protein

Cdc7 is an essential kinase required for the initiation of eukaryotic DNA replication. Previous studies in many species showed that the minichromosome maintenance complex is a major physiological target of this kinase. In this study, we have mapped the sites in human Mcm2 protein that are phosphoryl...

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Autors principals: Cho, Won-Ho, Lee, Young-Joo, Kong, Soo-Im, Hurwitz, Jerard, Lee, Joon-Kyu
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544202/
https://ncbi.nlm.nih.gov/pubmed/16864800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604990103
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