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Barttin modulates trafficking and function of ClC-K channels

Barttin is an accessory subunit of a subgroup of ClC-type chloride channels expressed in renal and inner ear epithelia. In this study, we examined the effects of barttin on two ClC-K channel isoforms, rat ClC-K1 and human ClC-Kb, using heterologous expression, patch clamping, confocal imaging, and f...

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Autores principales: Scholl, Ute, Hebeisen, Simon, Janssen, Audrey G. H., Müller-Newen, Gerhard, Alekov, Alexi, Fahlke, Christoph
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544099/
https://ncbi.nlm.nih.gov/pubmed/16849430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601631103
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