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The cannabinoid WIN 55,212-2 inhibits transient receptor potential vanilloid 1 (TRPV1) and evokes peripheral antihyperalgesia via calcineurin

Cannabinoids can evoke antihyperalgesia and antinociception at a peripheral site of action. However, the signaling pathways mediating these effects are not clearly understood. We tested the hypothesis that certain cannabinoids directly inhibit peripheral capsaicin-sensitive nociceptive neurons by de...

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Hlavní autoři: Patwardhan, Amol M., Jeske, Nathaniel A., Price, Theodore J., Gamper, Nikita, Akopian, Armen N., Hargreaves, Kenneth M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544096/
https://ncbi.nlm.nih.gov/pubmed/16849427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0603861103
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