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Heritable and stable gene knockdown in rats

The rat has served as an excellent model for studies on animal physiology and as a model for human diseases such as diabetes and alcoholism; however, genetic studies have been limited because of the inability to knock out genes. Our goal was to produce heritable deficiencies in specific gene functio...

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Autors principals: Dann, Christina Tenenhaus, Alvarado, Alma L., Hammer, Robert E., Garbers, David L.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544073/
https://ncbi.nlm.nih.gov/pubmed/16844779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604657103
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