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Topoisomerase IIIα and Bloom’s helicase can resolve a mobile double Holliday junction substrate through convergent branch migration

It has long been suspected that a double Holliday junction (dHJ) could be resolved by a topoisomerase partnered with a helicase by convergent branch migration of the HJs. Genetic analysis of yeast TOP3 and SGS1 has lent considerable evidence to the notion that the protein products of these genes are...

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Hlavní autoři: Plank, Jody L., Wu, Jianhong, Hsieh, Tao-shih
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1544052/
https://ncbi.nlm.nih.gov/pubmed/16849422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0604873103
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