Essentiality of clpX, but Not clpP, clpL, clpC, or clpE, in Streptococcus pneumoniae R6

We show by using a regulated promoter that clpX of Streptococcus pneumoniae R6 is essential, whereas clpP, clpL, clpC, and clpE can be disrupted. The essentiality of clpX was initially missed because of duplication and rearrangement in the region of the chromosome containing clpX. Depletion of ClpX...

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Veröffentlicht in:	J Bacteriol
Hauptverfasser:	Robertson, Gregory T., Ng, Wai-Leung, Gilmour, Raymond, Winkler, Malcolm E.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 2003
Schlagworte:	Molecular Biology of Pathogens
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC154392/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12700276/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JB.185.9.2961-2966.2003
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