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Brominated 7-hydroxycoumarin-4-ylmethyls: Photolabile protecting groups with biologically useful cross-sections for two photon photolysis

Photochemical release (uncaging) of bioactive messengers with three-dimensional spatial resolution in light-scattering media would be greatly facilitated if the photolysis could be powered by pairs of IR photons rather than the customary single UV photons. The quadratic dependence on light intensity...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Furuta, Toshiaki, Wang, Samuel S.-H., Dantzker, Jami L., Dore, Timothy M., Bybee, Wendy J., Callaway, Edward M., Denk, Winfried, Tsien, Roger Y.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1999
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15439/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9990000/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.4.1193
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