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Overexpression of angiotensin II type I receptor in cardiomyocytes induces cardiac hypertrophy and remodeling

Angiotensin II (AII) is a major determinant of arterial pressure and volume homeostasis, mainly because of its vascular action via the AII type 1 receptor (AT1R). AII has also been implicated in the development of cardiac hypertrophy because angiotensin I-converting enzyme inhibitors and AT1R antago...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Paradis, Pierre, Dali-Youcef, Nassim, Paradis, François W., Thibault, Gaétan, Nemer, Mona
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15433/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639182/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.931
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