A genetic model for a central (septum transversum) congenital diaphragmatic hernia in mice lacking Slit3

Congenital diaphragmatic hernia (CDH) is a significant cause of pediatric mortality in humans with a heterogeneous and poorly understood etiology. Here we show that mice lacking Slit3 developed a central (septum transversum) CDH. Slit3 encodes a member of the Slit family of guidance molecules and is...

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Bibliographic Details
Main Authors: Yuan, Wenlin, Rao, Yi, Babiuk, Randal P., Greer, John, Wu, Jane Y., Ornitz, David M.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2003
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC154325/
https://ncbi.nlm.nih.gov/pubmed/12702769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0730709100
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