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Chaperone action in the posttranslational topological reorientation of the hepatitis B virus large envelope protein: Implications for translocational regulation

The large L envelope protein of the hepatitis B virus utilizes a new folding pathway to acquire a dual transmembrane topology in the endoplasmic reticulum (ER). The process involves cotranslational membrane integration and subsequent posttranslational translocation of its preS subdomain into the ER....

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Detalhes bibliográficos
Main Authors: Lambert, Carsten, Prange, Reinhild
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC154322/
https://ncbi.nlm.nih.gov/pubmed/12697898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0930813100
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