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Abnormalities in the immune system of children with beta-thalassaemia major.

We have studied both the humoral and cell mediated immune systems of 23 children with beta-thalassaemia major. In children who had not been splenectomized, a 3-fold expansion in the number of circulating B cells and a modest polyclonal gammopathy was present. Of these patients 70% had decreased numb...

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Huvudupphovsmän: Dwyer, J, Wood, C, McNamara, J, Williams, A, Andiman, W, Rink, L, O'Connor, T, Pearson, H
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1987
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1542746/
https://ncbi.nlm.nih.gov/pubmed/3498580
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