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Constraining the subunit order of rod cyclic nucleotide-gated channels reveals a diagonal arrangement of like subunits

Retinal rod cyclic nucleotide-gated channels are composed of α and β subunits. We have explored possible subunit arrangements by expressing tandemly linked dimers of both subunits and examining their responses to three different modulating agents. Channels formed from either α-β or β-α heterodimers...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: He, Yejun, Ruiz, MariaLuisa, Karpen, Jeffrey W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15427/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10639176/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.97.2.895
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