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The role of reactive oxygen intermediates in nonspecific monocyte cytotoxicity induced by immune complexes.

Normal human monocytes were induced to lyse nonsensitized target cells when triggered by precipitating immune complexes (IC) or soluble heat-aggregated IgG (HAIgG). Catalase, azide, cyanide and three aminoacids employed as quenchers of ClO, significantly inhibited this nonspecific cytotoxicity (NSC)...

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Detalhes bibliográficos
Main Authors: Geffner, J R, Giordano, M, Serebrinsky, G, Isturiz, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1542611/
https://ncbi.nlm.nih.gov/pubmed/3038442
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