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High prevalence of antibodies to histones among patients with primary biliary cirrhosis.

Histones are small, basic proteins involved in the packing of DNA into the eucaryotic nucleus. Using an immunodot assay and an enzyme-linked immunosorbent assay (ELISA), sera from patients with liver disease were tested for antibodies to the five individual histones H1, H2A, H2B, H3 and H4. Histones...

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Detalhes bibliográficos
Main Authors: Penner, E, Muller, S, Zimmermann, D, Van Regenmortel, M H
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1542228/
https://ncbi.nlm.nih.gov/pubmed/3500816
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