Use of monoclonal antibodies to identify shared idiotypes on anticardiolipin and anti-DNA antibodies in human sera.

Using hybridoma technology we produced monoclonal antibodies (MoAb) to idiotypic determinants on human anti-cardiolipin antibodies purified from a patient with SLE. Hybridomas were screened by inhibition of cardiolipin binding activity of sera from patients with SLE. Seven hybridomas were selected,...

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Bibliografiske detaljer
Main Authors: Valesini, G, Tincani, A, Harris, E N, Mantelli, P G, Allegri, F, Palmieri, G, Hughes, G R, Balsano, F, Balestrieri, G
Format: Artigo
Sprog:Inglês
Udgivet: 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1542216/
https://ncbi.nlm.nih.gov/pubmed/3500812
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