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Impaired phorbol ester and calcium ionophore induced proliferation of T cells from old humans.

Current models of T cell activation implicate increases in intracellular free Ca2+ concentration and activation of the Ca2+ and phospholipid dependent enzyme protein kinase C (PKC) as important early events leading to interleukin 2 (IL-2) production, interleukin 2 receptor (IL-2R) expression, and su...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chopra, R K, Nagel, J E, Chrest, F J, Adler, W H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1542072/
https://ncbi.nlm.nih.gov/pubmed/3123107
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