Detection of autoantibodies in a quantitative immunoassay using recombinant ribonucleoprotein antigens.

A human cDNA expression library was screened with anti-ribonucleoprotein (RNP) antibodies from patients with connective tissue diseases. Three cDNA clones were isolated encoding 70 kD, A and B" ribonucleoprotein autoantigens which were expressed as beta-galactosidase fusion proteins. Antigens w...

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Bibliographic Details
Main Authors: Habets, W J, Hoet, M H, Sillekens, P T, De Rooij, D J, Van de Putte, L B, Van Venrooij, W J
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1541836/
https://ncbi.nlm.nih.gov/pubmed/2527098
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