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Differential isotype recognition of two centromere associated polypeptides by immunoblotting in connective tissue disease.

On investigating the immunoblotting profile of 65 systemic sclerosis patients, a 140 kD polypeptide was recognised by sera from 16, when immunoblotted against a nuclear-enriched K562 cell sonicate. All 16 sera contained anticentromere antibodies (ACA) detected by immunofluorescence (IF) and 15 of 16...

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Main Authors: McHugh, N J, James, I E, Maddison, P J
Formato: Artigo
Idioma:Inglês
Publicado: 1988
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1541583/
https://ncbi.nlm.nih.gov/pubmed/3048806
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