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Antibody-mediated proliferation of proximal tubule cells requires cross-linking of antigenic determinants.
In Heymann nephritis, the deposition in vivo of divalent anti-brush border antibodies on the luminal plasma membrane of proximal tubules leads to both epithelial cell proliferation and clumping and loss of microvilli. The passive transfer of divalent rat, sheep or rabbit anti-brush border antibodies...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
1988
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1541522/ https://ncbi.nlm.nih.gov/pubmed/2457465 |
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