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Trastuzumab, an appropriate first-line single-agent therapy for HER2-overexpressing metastatic breast cancer

Overexpression of the HER2/Neu (ErbB2) proto-oncogene is associated with breast cancer progression and poor patient prognosis. Herceptin (trastuzumab) is a humanized IgG1 against the ectodomain of the HER2 receptor. In combination with chemotherapy, it induces regression of HER2-overexpressing metas...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awdur: Arteaga, Carlos L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2003
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC154152/
https://ncbi.nlm.nih.gov/pubmed/12631388
Tagiau: Ychwanegu Tag
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