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Trastuzumab, an appropriate first-line single-agent therapy for HER2-overexpressing metastatic breast cancer

Overexpression of the HER2/Neu (ErbB2) proto-oncogene is associated with breast cancer progression and poor patient prognosis. Herceptin (trastuzumab) is a humanized IgG1 against the ectodomain of the HER2 receptor. In combination with chemotherapy, it induces regression of HER2-overexpressing metas...

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Bibliografske podrobnosti
Glavni avtor: Arteaga, Carlos L
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2003
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC154152/
https://ncbi.nlm.nih.gov/pubmed/12631388
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